An interaction between <it>Nrf2 </it>polymorphisms and smoking status affects annual decline in FEV<sub>1</sub>: a longitudinal retrospective cohort study

<p>Abstract</p> <p>Background</p> <p>An Nrf2-dependent response is a central protective mechanism against oxidative stress. We propose that particular genetic variants of the <it>Nrf2 </it>gene may be associated with a rapid forced expiratory volume in one s...

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Bibliographic Details
Main Authors: Hirota Tomomitsu, Noguchi Emiko, Iijima Hiroaki, Naito Takashi, Kaneko Yoshiko, Sakamoto Tohru, Masuko Hironori, Tamari Mayumi, Hizawa Nobuyuki
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/12/97