Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.

Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.

UDP-glucuronosyltransferases (UGTs), the most important enzymes in body detoxification and homeostasis maintaining, govern the glucuronidation reaction of various endogenous and environmental carcinogens. The metabolic function of UGTs can be severely influenced by hepatocellular carcinoma (HCC), th...

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Bibliographic Details
Main Authors: Linlin Lu, Juan Zhou, Jian Shi, Xiao-juan Peng, Xiao-xiao Qi, Ying Wang, Fang-Yuan Li, Fu-Yuan Zhou, Liang Liu, Zhong-Qiu Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4444081?pdf=render

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http://europepmc.org/articles/PMC4444081?pdf=render

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