Silica nanoparticle-exposure during neuronal differentiation modulates dopaminergic and cholinergic phenotypes in SH-SY5Y cells

Silica nanoparticle-exposure during neuronal differentiation modulates dopaminergic and cholinergic phenotypes in SH-SY5Y cells

Abstract Background Silica-ε-polycaprolactone-nanoparticles (SiPCL-NPs) represent a promising tool for laser-tissue soldering in the brain. After release of the SiPCL-NPs in the brain, neuronal differentiation might be modulated. The present study was performed to determine effects of SiPCL-NP-expos...

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Bibliographic Details
Main Authors: Linda Wiedmer, Angélique D. Ducray, Martin Frenz, Michael H. Stoffel, Hans-Rudolf Widmer, Meike Mevissen
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Nanobiotechnology
Subjects:
Neuronal differentiation
Phenotype
Nanomedicine
Toxicity
Polymeric-nanoparticles
Online Access:http://link.springer.com/article/10.1186/s12951-019-0482-2

Internet

http://link.springer.com/article/10.1186/s12951-019-0482-2

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