RANK/RANKL/OPG Signaling in the Brain: A Systematic Review of the Literature

Together with its dominant immunological and bone remodeling involvement, RRO axis, comprising of receptor activator of nuclear factor-κB (RANK), RANK ligand (RANKL), and osteoprotegerin (OPG) signaling, is as well-implicated in CNS functioning and corresponding pathologies. The CNS aspects of RANKL...

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Bibliographic Details
Main Authors: Anton Glasnović, Niall O'Mara, Nataša Kovačić, Danka Grčević, Srećko Gajović
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.590480/full