Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and thereby for humoral immunity.

Bibliographic Details
Main Authors: Simona Infantino, Amanda Light, Kristy O’Donnell, Vanessa Bryant, Danielle T. Avery, Michael Elliott, Stuart G. Tangye, Gabrielle Belz, Fabienne Mackay, Stephane Richard, David Tarlinton
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01009-1

Internet

https://doi.org/10.1038/s41467-017-01009-1

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