TGFβ signaling-induced miRNA participates in autophagic regulation by targeting PRAS40 in mesenchymal subtype of glioblastoma

TGFβ signaling-induced miRNA participates in autophagic regulation by targeting PRAS40 in mesenchymal subtype of glioblastoma

Objective: Mesenchymal subtype of glioblastoma (mesGBM) is a refractory disease condition characterized by therapeutic failure and tumor recurrence. Hyperactive transforming growth factor-β (TGF-β) signaling could be a signature event in mesGBM, which leads to dysregulation of downstream targets and...

Full description

Bibliographic Details
Main Authors: Yingbin Xie, Luyue Chen, Junhu Zhou, Qixue Wang, Chao Yang, Can Xu, Xiangyu Fan, Yanli Tan, Yanan Wang, Chunsheng Kang, Chuan Fang
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-08-01
Series:Cancer Biology & Medicine
Subjects:
autophagy
glioblastoma
microrna
pras40
tgfβ signalling
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1673

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1673

Similar Items