A Phylogenetic Survey on the Structure of the HIV-1 Leader RNA Domain That Encodes the Splice Donor Signal

RNA splicing is a critical step in the human immunodeficiency virus type 1 (HIV-1) replication cycle because it controls the expression of the complex viral proteome. The major 5′ splice site (5′ss) that is positioned in the untranslated leader of the HIV-1 RNA transcript is of particular interest b...

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Bibliographic Details
Main Authors: Nancy Mueller, Atze T. Das, Ben Berkhout
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/8/7/200