Hierarchical cooperation of transcription factors from integration analysis of DNA sequences, ChIP-Seq and ChIA-PET data

Hierarchical cooperation of transcription factors from integration analysis of DNA sequences, ChIP-Seq and ChIA-PET data

Abstract Background Chromosomal architecture, which is constituted by chromatin loops, plays an important role in cellular functions. Gene expression and cell identity can be regulated by the chromatin loop, which is formed by proximal or distal enhancers and promoters in linear DNA (1D). Enhancers...

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Bibliographic Details
Main Authors: Ruimin Wang, Yunlong Wang, Xueying Zhang, Yaliang Zhang, Xiaoyong Du, Yaping Fang, Guoliang Li
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Genomics
Subjects:
Chromatin loop
Transcription factor cooperation
Hierarchy and dynamics
Enhancer
Promoter
Online Access:http://link.springer.com/article/10.1186/s12864-019-5535-2

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http://link.springer.com/article/10.1186/s12864-019-5535-2

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