The bicarbonate transporter is essential for Bacillus anthracis lethality.

In the pathogenic bacterium Bacillus anthracis, virulence requires induced expression of the anthrax toxin and capsule genes. Elevated CO2/bicarbonate levels, an indicator of the host environment, provide a signal ex vivo to increase expression of virulence factors, but the mechanism underlying indu...

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Bibliographic Details
Main Authors: Adam C Wilson, Magali Soyer, James A Hoch, Marta Perego
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2582132?pdf=render