Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients.

The micronutrients zinc, quercetin, butyrate, indole and berberine were evaluated for their ability to induce remodeling of epithelial tight junctions (TJs) and enhance barrier integrity in the CACO-2 gastrointestinal epithelial cell culture model. All five of these chemically very diverse micronutr...

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Bibliographic Details
Main Authors: Mary Carmen Valenzano, Katherine DiGuilio, Joanna Mercado, Mimi Teter, Julie To, Brendan Ferraro, Brittany Mixson, Isabel Manley, Valerissa Baker, Beverley A Moore, Joshua Wertheimer, James M Mullin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4520484?pdf=render