Evaluation of IRX Genes and Conserved Noncoding Elements in a Region on 5p13.3 Linked to Families with Familial Idiopathic Scoliosis and Kyphosis

Evaluation of IRX Genes and Conserved Noncoding Elements in a Region on 5p13.3 Linked to Families with Familial Idiopathic Scoliosis and Kyphosis

Because of genetic heterogeneity present in idiopathic scoliosis, we previously defined clinical subsets (a priori) from a sample of families with idiopathic scoliosis to find genes involved with spinal curvature. Previous genome-wide linkage analysis of seven families with at least two individuals...

Full description

Bibliographic Details
Main Authors: Cristina M. Justice, Kevin Bishop, Blake Carrington, Jim C. Mullikin, Kandice Swindle, Beth Marosy, Raman Sood, Nancy H. Miller, Alexander F. Wilson
Format: Article
Language:English
Published: Oxford University Press 2016-06-01
Series:G3: Genes, Genomes, Genetics
Subjects:
idiopathic scoliosis
IRX genes
zebrafish transgenesis
conserved noncoding regions
kyphoscoliosis
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.029975

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.029975

Similar Items