Ethanol extract of propolis and its constituent caffeic acid phenethyl ester inhibit breast cancer cells proliferation in inflammatory microenvironment by inhibiting TLR4 signal pathway and inducing apoptosis and autophagy

Ethanol extract of propolis and its constituent caffeic acid phenethyl ester inhibit breast cancer cells proliferation in inflammatory microenvironment by inhibiting TLR4 signal pathway and inducing apoptosis and autophagy

Abstract Background Propolis and its major constituent – caffeic acid phenethyl ester (CAPE) have good abilities on antitumor and anti-inflammation. However, little is known about the actions of propolis and CAPE on tumor in inflammatory microenvironment, and inflammatory responses play decisive rol...

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Bibliographic Details
Main Authors: Huasong Chang, Yuehua Wang, Xusheng Yin, Xinying Liu, Hongzhuan Xuan
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Propolis
Caffeic acid phenethyl ester
Anti-inflammatory
Antitumor
Toll like receptor 4
Online Access:http://link.springer.com/article/10.1186/s12906-017-1984-9

Internet

http://link.springer.com/article/10.1186/s12906-017-1984-9

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