Blood-Brain Barrier Disruption Induced Cognitive Impairment Is Associated With Increase of Inflammatory Cytokine

Blood-Brain Barrier Disruption Induced Cognitive Impairment Is Associated With Increase of Inflammatory Cytokine

Patients with diabetes suffer the higher risk of dementia and the underlying pathological mechanism of cognitive dysfunction in diabetes is not fully understood. In this study, we explore whether the cognitive impairment in the diabetic rat is associated with increased blood brain barrier (BBB) perm...

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Bibliographic Details
Main Authors: Jieli Geng, Liping Wang, Linyuan Zhang, Chuan Qin, Yaying Song, Yuanyuan Ma, Yajing Chen, Shengdi Chen, Yongting Wang, Zhijun Zhang, Guo-Yuan Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
cognitive impairment
blood-brain barrier
diabetes
tight junction
Morris water maze
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00129/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00129/full

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