Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties of TRMs remain unclear. Here, we use a unique human tissue resource to determine whether human tissue memory T cells constitute a distinct sub...

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Bibliographic Details
Main Authors: Brahma V. Kumar, Wenji Ma, Michelle Miron, Tomer Granot, Rebecca S. Guyer, Dustin J. Carpenter, Takashi Senda, Xiaoyun Sun, Siu-Hong Ho, Harvey Lerner, Amy L. Friedman, Yufeng Shen, Donna L. Farber
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
human immunology
memory T cells
RNA-seq
mucosal immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312202

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http://www.sciencedirect.com/science/article/pii/S2211124717312202

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