Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter.

BACKGROUND:Particulate matter (PM) pollutant exposure, which induces oxidative stress and inflammation, and vitamin D insufficiency, which compromises immune regulation, are detrimental in asthma. OBJECTIVES:Mechanistic cell culture experiments were undertaken to ascertain whether vitamin D abrogate...

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Bibliographic Details
Main Authors: Paul E Pfeffer, Haw Lu, Elizabeth H Mann, Yin-Huai Chen, Tzer-Ren Ho, David J Cousins, Chris Corrigan, Frank J Kelly, Ian S Mudway, Catherine M Hawrylowicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6114286?pdf=render