Hodgkin Lymphoma-Derived Extracellular Vesicles Change the Secretome of Fibroblasts Toward a CAF Phenotype

Hodgkin Lymphoma-Derived Extracellular Vesicles Change the Secretome of Fibroblasts Toward a CAF Phenotype

Secretion of extracellular vesicles (EVs) is a ubiquitous mechanism of intercellular communication based on the exchange of effector molecules, such as growth factors, cytokines, and nucleic acids. Recent studies identified tumor-derived EVs as central players in tumor progression and the establishm...

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Bibliographic Details
Main Authors: Bastian Dörsam, Teresa Bösl, Katrin S. Reiners, Sabine Barnert, Rolf Schubert, Olga Shatnyeva, Paola Zigrino, Andreas Engert, Hinrich P. Hansen, Elke Pogge von Strandmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
Hodgkin lymphoma
extracellular vesicles
tumor microenvironment
cancer-associated fibroblasts
NF-κB-signaling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01358/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01358/full

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