Phosphoproteomic Analysis of the Amygdala Response to Adolescent Glucocorticoid Exposure Reveals G-Protein Coupled Receptor Kinase 2 as a Target for Reducing Motivation for Alcohol

Phosphoproteomic Analysis of the Amygdala Response to Adolescent Glucocorticoid Exposure Reveals G-Protein Coupled Receptor Kinase 2 as a Target for Reducing Motivation for Alcohol

Early life stress is associated with risk for developing alcohol use disorders (AUDs) in adulthood. Though the neurobiological mechanisms underlying this vulnerability are not well understood, evidence suggests that aberrant glucocorticoid and noradrenergic system functioning play a role. The presen...

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Bibliographic Details
Main Authors: Megan L. Bertholomey, Kathryn Stone, TuKiet T. Lam, Seojin Bang, Wei Wu, Angus C. Nairn, Jane R. Taylor, Mary M. Torregrossa
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Proteomes
Subjects:
adolescence
corticosterone
proteomics
yohimbine
progressive ratio
reinstatement
ethanol
Online Access:http://www.mdpi.com/2227-7382/6/4/41

Internet

http://www.mdpi.com/2227-7382/6/4/41

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