Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.

Fermentation of these macromolecular food or pharmaceutical excipient ingredients by the gut microbiota leads to the formation of short chain fatty acids (SCFA) which can be absorbed from the gut into the general circulation. Circulating SFCA activate downstream effectors responsible for energy and...

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Bibliographic Details
Main Author: Shireesh Apte
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council
Series:Journal of Excipients and Food Chemicals
Online Access:http://jefc.scholasticahq.com/article/920-macromolecular-excipients-exert-biological-effects-via-their-microbial-fermentation-absorbable-products.pdf