Identification of introns harboring functional sequence elements through positional conservation

Abstract Many human introns carry out a function, in the sense that they are critical to maintain normal cellular activity. Their identification is fundamental to understanding cellular processes and disease. However, being noncoding elements, such functional introns are poorly predicted based on tr...

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Bibliographic Details
Main Authors: Michal Chorev, Alan Joseph Bekker, Jacob Goldberger, Liran Carmel
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04476-0