DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity.

Throughout its enzootic cycle, the Lyme disease spirochete Borreliella (Borrelia) burgdorferi, senses and responds to changes in its environment using a small repertoire of transcription factors that coordinate the expression of genes required for infection of Ixodes ticks and various mammalian host...

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Bibliographic Details
Main Authors: William K Boyle, Crystal L Richards, Daniel P Dulebohn, Amanda K Zalud, Jeff A Shaw, Sándor Lovas, Frank C Gherardini, Travis J Bourret
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009072