Identification of multiple proteoforms biomarkers on clinical samples by routine Top-Down approaches

Top-Down approaches have an extremely high biological relevance, especially when it comes to biomarker discovery, but the necessary pre-fractionation constraints are not easily compatible with the robustness requirements and the size of clinical sample cohorts. We have demonstrated that intact prote...

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Bibliographic Details
Main Authors: Jerome Vialaret, Pierre-Olivier Schmit, Sylvain Lehmann, Audrey Gabelle, Jason Wood, Marshall Bern, Rainer Paape, Detlev Suckau, Gary Kruppa, Christophe Hirtz
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918303275