Fusion tags for protein solubility, purification and immunogenicity in Escherichia coli: The novel Fh8 system

Proteins are now widely produced in diverse microbial cell factories. The Escherichia coli is still the dominant host for recombinant protein production but, as a bacterial cell, it also has its issues: the aggregation of foreign proteins into insoluble inclusion bodies is perhaps the main limiting...

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Bibliographic Details
Main Authors: Sofia eCosta, André eAlmeida, António eCastro, Lucília eDomingues
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00063/full