FoxP3-miR-150-5p/3p suppresses ovarian tumorigenesis via an IGF1R/IRS1 pathway feedback loop

FoxP3-miR-150-5p/3p suppresses ovarian tumorigenesis via an IGF1R/IRS1 pathway feedback loop

Abstract Ovarian cancer (OC) causes more deaths than any other gynecological cancer. Many cellular pathways have been elucidated to be associated with OC development and progression. Specifically, the insulin-like growth factor 1 receptor/insulin receptor substrate 1 (IGF1R/IRS1) pathway participate...

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Bibliographic Details
Main Authors: Qinkai Zhang, Xunzhu Zhou, Maoping Wan, Xixi Zeng, Jiarong Luo, Yesha Xu, Liying Ji, Jian-An Zhang, Pei Fan, Jianing Zhong, Jianmin Wu
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03554-6

Internet

https://doi.org/10.1038/s41419-021-03554-6

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