Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae

Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae

Attributed to the tropism for host microvascular endothelium lining the blood vessels, vascular inflammation and dysfunction represent salient features of rickettsial pathogenesis, yet the details of fundamentally important pathogen interactions with host endothelial cells (ECs) as the primary targe...

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Bibliographic Details
Main Authors: Abha Sahni, Hema P. Narra, Sanjeev K. Sahni
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Akt (protein kinase B)
endothelial cells
mTOR
protein kinase C
Rickettsia
Online Access:https://www.mdpi.com/1422-0067/21/19/7179

Internet

https://www.mdpi.com/1422-0067/21/19/7179

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