New Insights Into X-Chromosome Reactivation during Reprogramming to Pluripotency

Dosage compensation between the sexes results in one X chromosome being inactivated during female mammalian development. Chromosome-wide transcriptional silencing from the inactive X chromosome (Xi) in mammalian cells is erased in a process termed X-chromosome reactivation (XCR), which has emerged a...

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Bibliographic Details
Main Authors: Amitesh Panda, Jan J. Zylicz, Vincent Pasque
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
XCR
XCI
Online Access:https://www.mdpi.com/2073-4409/9/12/2706