The NLRP3 inflammasome mediates liver failure by activating procaspase-1 and pro-IL-1 β and regulating downstream CD40-CD40L signaling

Objectives In this prospective case–control study, we explored the regulatory roles of the NLRP3 inflammasome in hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF). Methods Thirty patients with HBV-ACLF, 30 patients with chronic hepatitis B, and 30 healthy individuals were enroll...

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Bibliographic Details
Main Authors: Zenghui Li, Jianning Jiang
Format: Article
Language:English
Published: SAGE Publishing 2021-09-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605211036845