Prediction of polyproline II secondary structure propensity in proteins

Background: The polyproline II helix (PPIIH) is an extended protein left-handed secondary structure that usually but not necessarily involves prolines. Short PPIIHs are frequently, but not exclusively, found in disordered protein regions, where they may interact with peptide-binding domains. However...

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Bibliographic Details
Main Authors: Kevin T. O’Brien, Catherine Mooney, Cyril Lopez, Gianluca Pollastri, Denis C. Shields
Format: Article
Language:English
Published: The Royal Society 2020-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191239