Stromal microenvironment processes unveiled by biological component analysis of gene expression in xenograft tumor models

<p>Abstract</p> <p>Background</p> <p>Mouse xenograft models, in which human cancer cells are implanted in immune-suppressed mice, have been popular for studying the mechanisms of novel therapeutic targets, tumor progression and metastasis. We hypothesized that we could...

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Bibliographic Details
Main Authors: Chen James L, Huang Yong, Lee Younghee, Yang Xinan, Xing Rosie H, Lussier Yves A
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/S9/S11