Long-chain saturated fatty acid species are not toxic to human pancreatic β-cells and may offer protection against pro-inflammatory cytokine induced β-cell death

Abstract Obesity is a major risk factor for type 2 diabetes (T2D) although the causal links remain unclear. A feature shared by both conditions however is systemic inflammation and raised levels of circulating fatty acids (FFA). It is widely believed that in obese individuals genetically prone to T2...

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Bibliographic Details
Main Authors: Patricia Thomas, Kaiyven A. Leslie, Hannah J. Welters, Noel G. Morgan
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Nutrition & Metabolism
Subjects:
Online Access:https://doi.org/10.1186/s12986-021-00541-8