A receptor dependent-4D QSAR approach to predict the activity of mutated enzymes

Abstract Screening and selection tools to obtain focused libraries play a key role in successfully engineering enzymes of desired qualities. The quality of screening depends on efficient assays; however, a focused library generated with a priori information plays a major role in effectively identify...

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Bibliographic Details
Main Authors: R. Pravin Kumar, Naveen Kulkarni
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06625-x