Upregulated Expression of Macrophage Migration Inhibitory Factor, Its Analogue D-Dopachrome Tautomerase, and the CD44 Receptor in Peripheral CD4 T Cells from Clinically Isolated Syndrome Patients with Rapid Conversion to Clinical Defined Multiple Sclerosis

Upregulated Expression of Macrophage Migration Inhibitory Factor, Its Analogue D-Dopachrome Tautomerase, and the CD44 Receptor in Peripheral CD4 T Cells from Clinically Isolated Syndrome Patients with Rapid Conversion to Clinical Defined Multiple Sclerosis

<i>Background and objectives</i>: Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT) are two pleiotropic and primarily, but not exclusively, proinflammatory cytokines belonging to the MIF family of cytokines that have recently been shown to be implicated in t...

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Bibliographic Details
Main Authors: Eugenio Cavalli, Emanuela Mazzon, Maria Sofia Basile, Katia Mangano, Roberto Di Marco, Placido Bramanti, Ferdinando Nicoletti, Paolo Fagone, Maria Cristina Petralia
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Medicina
Subjects:
macrophage migration inhibitory factor
d-dopachrome tautomerase
multiple sclerosis
cd4<sup>+</sup> t cells
Online Access:https://www.mdpi.com/1010-660X/55/10/667

Internet

https://www.mdpi.com/1010-660X/55/10/667

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