Grape Seed Proanthocyanidin Extract Ameliorates Diabetic Bladder Dysfunction via the Activation of the Nrf2 Pathway.

Diabetes Mellitus (DM)-induced bladder dysfunction is predominantly due to the long-term oxidative stress caused by hyperglycemia. Grape seed proanthocyanidin extract (GSPE) has been reported to possess a broad spectrum of pharmacological and therapeutic properties against oxidative stress. However,...

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Bibliographic Details
Main Authors: Shouzhen Chen, Yaofeng Zhu, Zhifeng Liu, Zhaoyun Gao, Baoying Li, Dongqing Zhang, Zhaocun Zhang, Xuewen Jiang, Zhengfang Liu, Lingquan Meng, Yue Yang, Benkang Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4431834?pdf=render