Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein.

Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein.

The essential process of dosage compensation is required to equalize gene expression of X-chromosome genes between males (XY) and females (XX). In Drosophila, the conserved Male-specific lethal (MSL) histone acetyltransferase complex mediates dosage compensation by increasing transcript levels from...

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Bibliographic Details
Main Authors: Jennifer Urban, Guray Kuzu, Sarah Bowman, Benjamin Scruggs, Telmo Henriques, Robert Kingston, Karen Adelman, Michael Tolstorukov, Erica Larschan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5659772?pdf=render

Internet

http://europepmc.org/articles/PMC5659772?pdf=render

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