Estrogen Inhibits Colon Polyp Formation by Reducing Angiogenesis in a Carcinogen-Induced Rat Model

Objective. To study the effects of estrogen on colon polyp formation, proliferation, and angiogenesis on a rat model of colon cancer induced by dimethylhydrazine (DMH). Methods. Thirty-six female ovariectomized (OVX) rats were randomly divided into 3 groups: (I) control group (administrated with veh...

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Bibliographic Details
Main Authors: Jia Yang, Li-juan Xiong, Fei Xu, Xiang Zhao, Bo Liu, Kai-Lin Cai, Guo-bin Wang
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/453898