Common genetic variations in the NALP3 inflammasome are associated with delayed apoptosis of human neutrophils.

Common genetic variations in the NALP3 inflammasome are associated with delayed apoptosis of human neutrophils.

Neutrophils are key-players in the innate host defense and their programmed cell death and removal are essential for efficient resolution of inflammation. These cells recognize a variety of pathogens, and the NOD-like receptors (NLRs) have been suggested as intracellular sensors of microbial compone...

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Bibliographic Details
Main Authors: Robert Blomgran, Veronika Patcha Brodin, Deepti Verma, Ida Bergström, Peter Söderkvist, Christopher Sjöwall, Per Eriksson, Maria Lerm, Olle Stendahl, Eva Särndahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3293864?pdf=render

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http://europepmc.org/articles/PMC3293864?pdf=render

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