Drug affinity and targeted delivery: double functionalization of silk spheres for controlled doxorubicin delivery into Her2-positive cancer cells
Abstract Background The optimal drug delivery system should be biocompatible, biodegradable, and allow the sustained release of the drug only after it reaches the target cells. Silk, as a natural polymer, is a great candidate for building drug carriers. Genetically engineered silks offer the possibi...
Main Authors: | Kamil Kucharczyk, Anna Florczak, Tomasz Deptuch, Karolina Penderecka, Katarzyna Jastrzebska, Andrzej Mackiewicz, Hanna Dams-Kozlowska |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12951-020-00609-2 |
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