Inhibitory Receptors and Immune Checkpoints Regulating Natural Killer Cell Responses to Cancer

The discovery of immune checkpoints provided a breakthrough for cancer therapy. Immune checkpoints are inhibitory receptors that are up-regulated on chronically stimulated lymphocytes and have been shown to hinder immune responses to cancer. Monoclonal antibodies against the checkpoint molecules PD-...

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Bibliographic Details
Main Authors: Irina Buckle, Camille Guillerey
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/17/4263