Amplified and homozygously deleted genes in glioblastoma: impact on gene expression levels.

BACKGROUND: Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains unknown. METHODOLOGY: Single-nucleotide polymorphism (SNP)-arrays were used to determine the frequency of recurrent amplicons and h...

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Bibliographic Details
Main Authors: Inês Crespo, Hermínio Tão, Ana Belen Nieto, Olinda Rebelo, Patrícia Domingues, Ana Luísa Vital, Maria del Carmen Patino, Marcos Barbosa, Maria Celeste Lopes, Catarina Resende Oliveira, Alberto Orfao, María Dolores Tabernero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460955?pdf=render