Anti-hnRNP B1 (RA33) Autoantibodies Are Associated with the Clinical Phenotype in Russian Patients with Rheumatoid Arthritis and Systemic Sclerosis

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are potent autoantigenic targets in systemic autoimmune rheumatic diseases (SARD). Loss of tolerance to the RA33 complex consisting of hnRNP A2 and its alternatively spliced variants B1 and B2 has been the interest of rheumatologists. A novel ELISA f...

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Bibliographic Details
Main Authors: Aleksey Maslyanskiy, Natalya Lazareva, Polina Olinek, Peter Schierack, Christian Hentschel, Juliane Cuccato, Dimitrios P. Bogdanos, Sergey V. Lapin, Dirk Roggenbuck
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2014/516593