Role of Angiotensin II in Cardiovascular Disease — Therapeutic Implications of More Than a Century of Research

More than a century of research on the renin-angiotensin system (RAS) has uncovered the widespread involvement of angiotensin II (Ang II) in the pathophysiology of cardiovascular diseases. A number of outcomes-based mega trials utilising hard clinical endpoints have revealed beneficial effects of an...

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Bibliographic Details
Main Author: Carlos M Ferrario
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2006-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2006.003