Zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages.

Zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages.

BACKGROUND:Mouse krüppel-like factor 4 (Klf4) is a zinc finger-containing transcription factor required for terminal differentiation of goblet cells in the colon. However, studies using either Klf4(-/-) mice or mice with conditionally deleted Klf4 in their gastric epithelia showed different results...

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Bibliographic Details
Main Authors: I-Chen Li, Chein-Tso Chan, Yu-Fen Lu, Yi-Ting Wu, Yi-Chung Chen, Guo-Bin Li, Che-Yi Lin, Sheng-Ping L Hwang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3110806?pdf=render

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http://europepmc.org/articles/PMC3110806?pdf=render

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