MASH1/Ascl1a leads to GAP43 expression and axon regeneration in the adult CNS.

MASH1/Ascl1a leads to GAP43 expression and axon regeneration in the adult CNS.

Unlike CNS neurons in adult mammals, neurons in fish and embryonic mammals can regenerate their axons after injury. These divergent regenerative responses are in part mediated by the growth-associated expression of select transcription factors. The basic helix-loop-helix (bHLH) transcription factor,...

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Bibliographic Details
Main Authors: Ryan R Williams, Ishwariya Venkatesh, Damien D Pearse, Ava J Udvadia, Mary Bartlett Bunge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4353704?pdf=render

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http://europepmc.org/articles/PMC4353704?pdf=render

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