A Single Mutation N166D in Hemagglutinin Affects Antigenicity and Pathogenesis of H9N2 Avian Influenza Virus

A Single Mutation N166D in Hemagglutinin Affects Antigenicity and Pathogenesis of H9N2 Avian Influenza Virus

Some immune escape mutants of H9N2 virus and the corresponding mutations in hemagglutinin (HA) have been documented, but little is known about the impact of a single mutation on the antigenicity and pathogenesis of H9N2. In this study, seven critical sites in HA associated with the antigenicity were...

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Bibliographic Details
Main Authors: Fang Jin, Xiaomei Dong, Zhimin Wan, Dan Ren, Min Liu, Tuoyu Geng, Jianjun Zhang, Wei Gao, Hongxia Shao, Aijian Qin, Jianqiang Ye
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Viruses
Subjects:
H9N2
escape mutant
HA
N166D
antigenicity
pathogenesis
Online Access:https://www.mdpi.com/1999-4915/11/8/709

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https://www.mdpi.com/1999-4915/11/8/709

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