Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.

Short-chain fatty acids (SCFAs), primarily acetate, propionate, and butyrate, are metabolites formed by gut microbiota from complex dietary carbohydrates. Butyrate and acetate were reported to protect against diet-induced obesity without causing hypophagia, while propionate was shown to reduce food...

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Bibliographic Details
Main Authors: Hua V Lin, Andrea Frassetto, Edward J Kowalik, Andrea R Nawrocki, Mofei M Lu, Jennifer R Kosinski, James A Hubert, Daphne Szeto, Xiaorui Yao, Gail Forrest, Donald J Marsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323649?pdf=render