Multiscale modelling of cerebrovascular injury reveals the role of vascular anatomy and parenchymal shear stresses

Abstract Neurovascular injury is often observed in traumatic brain injury (TBI). However, the relationship between mechanical forces and vascular injury is still unclear. A key question is whether the complex anatomy of vasculature plays a role in increasing forces in cerebral vessels and producing...

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Bibliographic Details
Main Authors: Siamak Farajzadeh Khosroshahi, Xianzhen Yin, Cornelius K. Donat, Aisling McGarry, Maria Yanez Lopez, Nicoleta Baxan, David J. Sharp, Magdalena Sastre, Mazdak Ghajari
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92371-0