A novel side-chain orientation dependent potential derived from random-walk reference state for protein fold selection and structure prediction.

An accurate potential function is essential to attack protein folding and structure prediction problems. The key to developing efficient knowledge-based potential functions is to design reference states that can appropriately counteract generic interactions. The reference states of many knowledge-ba...

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Bibliographic Details
Main Authors: Jian Zhang, Yang Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2965178?pdf=render