COMP and TSP-4: Functional Roles in Articular Cartilage and Relevance in Osteoarthritis

COMP and TSP-4: Functional Roles in Articular Cartilage and Relevance in Osteoarthritis

Osteoarthritis (OA) is a slow-progressing joint disease, leading to the degradation and remodeling of the cartilage extracellular matrix (ECM). The usually quiescent chondrocytes become reactivated and accumulate in cell clusters, become hypertrophic, and intensively produce not only degrading enzym...

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Bibliographic Details
Main Authors: Kathrin Maly, Enrique Andres Sastre, Eric Farrell, Andrea Meurer, Frank Zaucke
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
COMP
TSP-4
extracellular matrix
articular cartilage
osteoarthritis
Online Access:https://www.mdpi.com/1422-0067/22/5/2242

Internet

https://www.mdpi.com/1422-0067/22/5/2242

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