Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds

Echinococcosis is a serious helminthic zoonosis with a great impact on human health and livestock husbandry. However, the clinically used drugs (benzimidazoles) have a low cure rate, so alternative drugs are urgently needed. Currently, drug screenings for echinococcosis are mainly phenotype-based, a...

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Bibliographic Details
Main Authors: Congshan Liu, Jianhai Yin, Jiaqing Yao, Zhijian Xu, Yi Tao, Haobing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00118/full