Functional role of G9a histone modifying enzymes in cancer

Post-translational modifications of DNA and histones are epigenetic mechanisms which affect the chromatin structure, ultimately regulating gene expression. Different epigenetic enzymes are actively involved in the addition or the removal of various covalent modifications which include acetylation, m...

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Bibliographic Details
Main Authors: Francesco eCasciello, Karolina eWindloch, Frank eGannon, Jason S Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
G9a
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00487/full