ERK-mediated autophagy promotes inactivated Sendai virus (HVJ-E)-induced apoptosis in HeLa cells in an Atg3-dependent manner

Abstract Background Apoptosis and autophagy are known to play important roles in cancer development. It has been reported that HVJ-E induces apoptosis in cancer cells, thereby inhibiting the development of tumors. To define the mechanism by which HVJ-E induces cell death, we examined whether HVJ-E a...

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Bibliographic Details
Main Authors: Tao Wang, Ning Yu, Miao Qian, Jie Feng, Shuyang Cao, Jun Yin, Quan Zhang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cancer Cell International
Subjects:
ERK
Online Access:http://link.springer.com/article/10.1186/s12935-018-0692-y